Infarct in the Heart: What’s MMP-9 Got to Do with It?

Infarct in the Heart: What’s MMP-9 Got to Do with It?

Over the past three decades, numerous studies have shown a strong connection between matrix metalloproteinase 9 (MMP-9) levels and myocardial infarction (MI) mortality and left ventricle remodeling and dysfunction. Despite this fact, clinical trials using MMP-9 inhibitors have been disappointing. Th...

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Bibliographic Details
Main Authors: Mediha Becirovic-Agic, Upendra Chalise, Michael J. Daseke, Shelby Konfrst, Jeffrey D. Salomon, Paras K. Mishra, Merry L. Lindsey
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
inflammation
extracellular matrix
matrix metalloproteinases
remodeling
macrophage
neutrophil
Online Access:https://www.mdpi.com/2218-273X/11/4/491

Internet

https://www.mdpi.com/2218-273X/11/4/491

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