Anti-fibrotic effect of Aliskiren in rats with deoxycorticosterone induced myocardial fibrosis and its potential mechanism

The objective of our study was to investigate the effect of Aliskiren, a renin inhibitor, on the deoxycorticosterone (DOCA) induced myocardial fibrosis in a rat model and its underlying mechanism. A total of 45 Sprague-Dawley (SD) rats underwent right nephrectomy and were randomly assigned into 3 gr...

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Bibliographic Details
Main Authors: Likun Ma, Jinsheng Hua, Lifeng He, Qian Li, Junling Zhou, Jiangtao Yu
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2012-05-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Online Access:http://www.bjbms.org/ojs/index.php/bjbms/article/view/2498