Leishmaniasis and glycosaminoglycans: a future therapeutic strategy?

Abstract Leishmania spp. depend on effective macrophage infection to establish and develop in mammalian hosts. Both metacyclic promastigotes and amastigotes are able to infect host cells, and thus they rely on several ligands that, when recognized by macrophage receptors, mediate parasite uptake. Du...

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Bibliographic Details
Main Authors: Débora Almeida Merida-de-Barros, Suzana Passos Chaves, Celso Luis Ribeiro Belmiro, João Luiz Mendes Wanderley
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-018-2953-y