Regulation of skeletal muscle mitochondrial activity by thyroid hormones: focus on "old" triiodothyronine and the "emerging" 3,5-diiodothyronine".

Regulation of skeletal muscle mitochondrial activity by thyroid hormones: focus on "old" triiodothyronine and the "emerging" 3,5-diiodothyronine".

3,5,3'-triiodo-L-thyronine (T3) plays a crucial role in regulating metabolic rate and fuel oxidation; however, the mechanisms by which it affects whole-body energy metabolism are still not completely understood. Skeletal muscle (SKM) plays a relevant role in energy metabolism and responds to th...

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Bibliographic Details
Main Authors: Assunta eLombardi, Maria eMoreno, Pieter eDe Lange, Susanna eIossa, Rosa Anna eBusiello, Fernando eGoglia
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Physiology
Subjects:
Diiodothyronines
Lipid Metabolism
Mitochondria
Thyroid Hormones
Uncoupling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00237/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00237/full

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