Exenatide Reduces Tumor Necrosis Factor-α-induced Apoptosis in Cardiomyocytes by Alleviating Mitochondrial Dysfunction

Exenatide Reduces Tumor Necrosis Factor-α-induced Apoptosis in Cardiomyocytes by Alleviating Mitochondrial Dysfunction

Background: Tumor necrosis factor-α (TNF-α) plays an important role in progressive contractile dysfunction in several cardiac diseases. The cytotoxic effects of TNF-α are suggested to be partly mediated by reactive oxygen species (ROS)- and mitochondria-dependent apoptosis. Glucagon-like peptide-1 (...

Full description

Bibliographic Details
Main Authors: Yuan-Yuan Cao, Zhang-Wei Chen, Yan-Hua Gao, Xing-Xu Wang, Jian-Ying Ma, Shu-Fu Chang, Ju-Ying Qian, Jun-Bo Ge
Format: Article
Language:English
Published: Wolters Kluwer 2015-01-01
Series:Chinese Medical Journal
Subjects:
Cell Apoptosis; Glucagon-like Peptide-1; Mitochondrial Function; Oxidative Stress; Tumor Necrosis Factor-α
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=23;spage=3211;epage=3218;aulast=Cao

Internet

http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=23;spage=3211;epage=3218;aulast=Cao

Similar Items