A novel asymmetric synthesis of cinacalcet hydrochloride

A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described.

Bibliographic Details
Main Authors: Veera R. Arava, Laxminarasimhulu Gorentla, Pramod K. Dubey
Format: Article
Language:English
Published: Beilstein-Institut 2012-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.158