Synergistic Antimyeloma Activity of Dendritic Cells and Pomalidomide in a Murine Myeloma Model

Synergistic Antimyeloma Activity of Dendritic Cells and Pomalidomide in a Murine Myeloma Model

We have previously shown that immunization with tumor antigen-loaded dendritic cells (DCs) and the immunomodulating drug, lenalidomide, synergistically potentiates the enhancing antitumor immunity in a myeloma mouse model. In this study, we investigated the immunogenicity of DCs combined with pomali...

Full description

Bibliographic Details
Main Authors: Manh-Cuong Vo, Seoyun Yang, Sung-Hoon Jung, Tan-Huy Chu, Hyun-Ju Lee, Thangaraj Jaya Lakshmi, Hye-Seong Park, Hyeoung-Joon Kim, Je-Jung Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
dendritic cell
immunotherapy
pomalidomide
myeloma
cancer vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01798/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01798/full

Similar Items