Induced pluripotent stem cell models of lysosomal storage disorders

Induced pluripotent stem cell models of lysosomal storage disorders

Induced pluripotent stem cells (iPSCs) have provided new opportunities to explore the cell biology and pathophysiology of human diseases, and the lysosomal storage disorder research community has been quick to adopt this technology. Patient-derived iPSC models have been generated for a number of lys...

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Bibliographic Details
Main Authors: Daniel K. Borger, Benjamin McMahon, Tamanna Roshan Lal, Jenny Serra-Vinardell, Elma Aflaki, Ellen Sidransky
Format: Article
Language:English
Published: The Company of Biologists 2017-06-01
Series:Disease Models & Mechanisms
Subjects:
Gaucher disease
IPSC models
Lysosomal enzymes
Lysosomal storage disorders
Neurodegeneration
Online Access:http://dmm.biologists.org/content/10/6/691

Internet

http://dmm.biologists.org/content/10/6/691

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