Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice

Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice

Microglial healing peptide 1, “MHP1”, is a newly developed synthetic peptide composed of the DE and a part of the EF loop of the receptor activator of nuclear factor-кB (NFκB) ligand (RANKL). Our previous report demonstrated that MHP1 significantly inhibits Toll-like receptor (TLR) 2- and 4-induced...

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Main Authors: Munehisa Shimamura, Hironori Nakagami, Hideo Shimizu, Kouji Wakayama, Tomohiro Kawano, Yuka Ikeda, Hiroki Hayashi, Shota Yoshida, Hideki Mochizuki, Ryuichi Morishita
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/4637084

Internet

http://dx.doi.org/10.1155/2018/4637084

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