Control of Dichotomic Innate and Adaptive Immune Responses by Artery Tertiary Lymphoid Organs in Atherosclerosis

Control of Dichotomic Innate and Adaptive Immune Responses by Artery Tertiary Lymphoid Organs in Atherosclerosis

Tertiary lymphoid organs (TLOs) emerge in tissues in response to nonresolving inflammation such as chronic infection, graft rejection, and autoimmune disease. We identified artery TLOs (ATLOs) in the adventitia adjacent to atherosclerotic plaques of aged hyperlipidemic ApoE-/- mice. ATLOs are struct...

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Bibliographic Details
Main Authors: Falk eWeih, Rolf eGräbner, Desheng eHu, Michael eBeer, Andreas Johann Habenicht
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Physiology
Subjects:
Atherosclerosis
Autoimmunity
Inflammation
Adaptive Immune Responses
Artery Tertiary Lymphoid Organs
Stable Plaque
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00226/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00226/full

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