Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer.

Epigenetic processes--including DNA methylation--are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we investigate whether the intra-gene methylation...

Full description

Bibliographic Details
Main Authors: Thomas E Bartlett, Alexey Zaikin, Sofia C Olhede, James West, Andrew E Teschendorff, Martin Widschwendter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23874574/pdf/?tool=EBI