Development of double-positive thymocytes at single-cell resolution

Development of double-positive thymocytes at single-cell resolution

Abstract Background T cells generated from thymopoiesis are essential for the immune system, and recent single-cell studies have contributed to our understanding of the development of thymocytes at the genetic and epigenetic levels. However, the development of double-positive (DP) T cells, which com...

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Bibliographic Details
Main Authors: Young Li, Kun Li, Lianbang Zhu, Bin Li, Dandan Zong, Pengfei Cai, Chen Jiang, Pengcheng Du, Jun Lin, Kun Qu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Genome Medicine
Subjects:
Single-cell sequencing
Thymocyte
Cell cycle
Thymic selection
Online Access:https://doi.org/10.1186/s13073-021-00861-7

Internet

https://doi.org/10.1186/s13073-021-00861-7

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