Network-based prediction and analysis of HIV dependency factors.

HIV Dependency Factors (HDFs) are a class of human proteins that are essential for HIV replication, but are not lethal to the host cell when silenced. Three previous genome-wide RNAi experiments identified HDF sets with little overlap. We combine data from these three studies with a human protein in...

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Bibliographic Details
Main Authors: T M Murali, Matthew D Dyer, David Badger, Brett M Tyler, Michael G Katze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3178628?pdf=render