Journey of TRAIL from bench to bedside and its potential role in immuno-oncology

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. Its selective ability to ac...

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Bibliographic Details
Main Authors: George E. Naoum, Donald J. Buchsbaum, Fady Tawadros, Ammad Farooqi, Waleed O. Arafat
Format: Article
Language:English
Published: PAGEPress Publications 2017-04-01
Series:Oncology Reviews
Subjects:
Online Access:http://www.oncologyreviews.org/index.php/or/article/view/332