A Natural Triterpene Derivative from Euphorbia kansui Inhibits Cell Proliferation and Induces Apoptosis against Rat Intestinal Epithelioid Cell Line in Vitro

A Natural Triterpene Derivative from Euphorbia kansui Inhibits Cell Proliferation and Induces Apoptosis against Rat Intestinal Epithelioid Cell Line in Vitro

Kansenone is a triterpene from the root of the traditional Chinese medicine, Euphorbia kansui. However, kansenone exerts serious toxicity, but the exact mechanism was not clear. In this work, the effects of kansenone on cell proliferation, cell cycle, cell damage, and cell apoptosis were investigate...

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Bibliographic Details
Main Authors: Fangfang Cheng, Yanjing Yang, Li Zhang, Yudan Cao, Weifeng Yao, Yuping Tang, Anwei Ding
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
kansenone
cell proliferation
cell damage
cell cycle
cell apoptosis
death receptor pathway
mitochondrial pathway
Online Access:http://www.mdpi.com/1422-0067/16/8/18956

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http://www.mdpi.com/1422-0067/16/8/18956

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