Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder.

Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder.

Previous studies of major depressive disorder (MDD) have focused on abnormalities in the prefrontal cortex and medial temporal regions. There has been little investigation in MDD of midbrain and subcortical regions central to reward/aversion function, such as the ventral tegmental area/substantia ni...

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Bibliographic Details
Main Authors: Anne J Blood, Dan V Iosifescu, Nikos Makris, Roy H Perlis, David N Kennedy, Darin D Dougherty, Byoung Woo Kim, Myung Joo Lee, Shirley Wu, Sang Lee, Jesse Calhoun, Steven M Hodge, Maurizio Fava, Bruce R Rosen, Jordan W Smoller, Gregory P Gasic, Hans C Breiter, Phenotype Genotype Project on Addiction and Mood Disorders
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2993928?pdf=render

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http://europepmc.org/articles/PMC2993928?pdf=render

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