Prediction of Necrotic Core and Hypoxic Zone of Multicellular Spheroids in a Microbioreactor with a U-Shaped Barrier

Microfluidic devices have been widely used for biological and cellular studies. Microbioreactors for three-dimensional (3D) multicellular spheroid culture are now considered as the next generation in in vitro diagnostic tools. The feasibility of using 3D cell aggregates to form multicellular spheroi...

Full description

Bibliographic Details
Main Authors: Maryam Barisam, Mohammad Said Saidi, Navid Kashaninejad, Nam-Trung Nguyen
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Micromachines
Subjects:
Online Access:http://www.mdpi.com/2072-666X/9/3/94