Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player

The classic neurotrophins Nerve Growth Factor (NGF), Brain Derived Neurotrophic Factor (BDNF) and Neurotrophins NT-3 and NT-4 are well known to regulate various aspects of neuronal differentiation, survival and growth. They do this by binding to their cognate receptors, members of the Tropomyosin-re...

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Bibliographic Details
Main Authors: Rachel eUren, Ann eTurnley
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Akt
NGF
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00039/full