SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation

SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation

<p>Abstract</p> <p>Background</p> <p>SPARC is a matricellular glycoprotein with growth-inhibitory and antiangiogenic activity in some cell types. The study of this protein in hematopoietic malignancies led to conflicting reports about its role as a tumor suppressor or p...

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Bibliographic Details
Main Authors: Giallongo Cesarina, La Cava Piera, Tibullo Daniele, Barbagallo Ignazio, Parrinello Nunziatina, Cupri Alessandra, Stagno Fabio, Consoli Carla, Chiarenza Annalisa, Palumbo Giuseppe A, Di Raimondo Francesco
Format: Article
Language:English
Published: BMC 2013-02-01
Series:BMC Cancer
Subjects:
CML
Imatinib
SPARC
Granulocytes
Monocytes
Online Access:http://www.biomedcentral.com/1471-2407/13/60

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http://www.biomedcentral.com/1471-2407/13/60

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