Impact on the Onset of Psychosis of a Polygenic Schizophrenia-Related Risk Score and Changes in White Matter Volume

Impact on the Onset of Psychosis of a Polygenic Schizophrenia-Related Risk Score and Changes in White Matter Volume

Background: Reductions in the volume of brain white matter are a common feature in schizophrenia and bipolar disorder while the association between white matter and polygenic schizophrenia-related risk is unclear. To look at the intermediate state between health and the full-blown disorder, we inves...

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Bibliographic Details
Main Authors: Fabienne Harrisberger, Renata Smieskova, Tobias Egli, Andor E. Simon, Anita Riecher-Rössler, Paolo Fusar-Poli, Andreas Papassotiropoulos, Stefan Borgwardt
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Psychosis
MRI
Polygenic schizophrenia-related risk
PSRS
Genetic risk
White matter
First episode psychosis
At-risk mental state
Clinical high risk
Schizophrenia
Transition
Imaging
Bipolar
Online Access:https://www.karger.com/Article/FullText/491986

Internet

https://www.karger.com/Article/FullText/491986

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