What’s Wrong in a Jump? Prediction and Validation of Splice Site Variants

What’s Wrong in a Jump? Prediction and Validation of Splice Site Variants

Alternative splicing (AS) is a crucial process to enhance gene expression driving organism development. Interestingly, more than 95% of human genes undergo AS, producing multiple protein isoforms from the same transcript. Any alteration (e.g., nucleotide substitutions, insertions, and deletions) inv...

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Bibliographic Details
Main Authors: Giulia Riolo, Silvia Cantara, Claudia Ricci
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Methods and Protocols
Subjects:
alternative splicing
splicing sites
splice variant
prediction tools
machine learning
experimental validation
Online Access:https://www.mdpi.com/2409-9279/4/3/62

Internet

https://www.mdpi.com/2409-9279/4/3/62

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