Cucurbitacin E Inhibits Huh7 Hepatoma Carcinoma Cell Proliferation and Metastasis via Suppressing MAPKs and JAK/STAT3 Pathways

Cucurbitacin E Inhibits Huh7 Hepatoma Carcinoma Cell Proliferation and Metastasis via Suppressing MAPKs and JAK/STAT3 Pathways

Cucurbitacin E (CuE), a highly oxygenated tetracyclic triterpene from Cucurbitaceae, has shown to exhibit potent cytotoxic and anti-proliferative properties against several human cancer cells. However, the underlying effects and mechanisms of CuE regarding hepatocellular carcinoma (HCC) have not bee...

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Bibliographic Details
Main Authors: Yang Liu, Heng Yang, Qiang Guo, Tingting Liu, Yong Jiang, Mingbo Zhao, Kewu Zeng, Pengfei Tu
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
cucurbitacin e
hepatocellular carcinoma
proliferation
migration
mapk pathway
jak/stat3 pathway
Online Access:https://www.mdpi.com/1420-3049/25/3/560

Internet

https://www.mdpi.com/1420-3049/25/3/560

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