Oxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer-Derived Cell Lines

Recently, the cytotoxic effects of apigenin (4′,5,7-trihydroxyflavone), particularly its marked inhibition of cancer cell viability both in vitro and in vivo, have attracted the attention of the anticancer drug discovery field. Despite this, there are few studies of apigenin in cervical cancer, and...

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Main Authors: Raquel P. Souza, Patrícia de S. Bonfim-Mendonça, Fabrícia Gimenes, Bianca A. Ratti, Vanessa Kaplum, Marcos L. Bruschi, Celso V. Nakamura, Sueli O. Silva, Silvya S. Maria-Engler, Marcia E. L. Consolaro
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/1512745