Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells

Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells

Butyric acid as a histone deacetylase (HDAC) inhibitor is produced by a number of periodontal and root canal microorganisms (such as <i>Porphyromonas</i>, <i>Fusobacterium</i>, etc.). Butyric acid may affect the biological activities of periodontal/periapical cells such as os...

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Bibliographic Details
Main Authors: Mei-Chi Chang, Yunn-Jy Chen, Yun-Chia Lian, Bei-En Chang, Chih-Chia Huang, Wei-Ling Huang, Yu-Hwa Pan, Jiiang-Huei Jeng
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
bone resorption
butyric acid
HDAC inhibitor
osteoblasts
osteoprotegerin/RANKL
periodontal/root canal pathogens
Online Access:https://www.mdpi.com/1422-0067/19/12/4071

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https://www.mdpi.com/1422-0067/19/12/4071

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