The CIITA genetic polymorphism rs4774*C in combination with the HLA-DRB1*15:01 allele as a putative susceptibility factor to multiple sclerosis in Brazilian females

The CIITA genetic polymorphism rs4774*C in combination with the HLA-DRB1*15:01 allele as a putative susceptibility factor to multiple sclerosis in Brazilian females

The objective of this study was to investigate the association between the HLA alleles at the DQA1, DQB1 and DRB1 loci, the CIITA genetic polymorphisms -168A/G and +1614G/C, and susceptibility to multiple sclerosis (MS) in a sample from Rio de Janeiro State, Brazil. Furthermore, we wished to determi...

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Bibliographic Details
Main Authors: Eduardo R. Paradela, Soniza V. Alves-Leon, André L. S. Figueiredo, Valéria C. S. R. Pereira, Fabíola Malfetano, Letícia F. Mansur, Simone Scherpenhuijzen, Luciana A. Agostinho, Catielly F. Rocha, Fernanda Rueda-Lopes, Emerson Gasparetto, Carmen L. A. Paiva
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2015-04-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
gene CIITA
HLA
rs4774*C
HLA-DRB1*15:01
esclerose múltipla
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000400283&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000400283&lng=en&tlng=en

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