PRD-2 directly regulates casein kinase I and counteracts nonsense-mediated decay in the Neurospora circadian clock

PRD-2 directly regulates casein kinase I and counteracts nonsense-mediated decay in the Neurospora circadian clock

Circadian clocks in fungi and animals are driven by a functionally conserved transcription–translation feedback loop. In Neurospora crassa, negative feedback is executed by a complex of Frequency (FRQ), FRQ-interacting RNA helicase (FRH), and casein kinase I (CKI), which inhibits the activity of the...

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Bibliographic Details
Main Authors: Christina M Kelliher, Randy Lambreghts, Qijun Xiang, Christopher L Baker, Jennifer J Loros, Jay C Dunlap
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
circadian clock
Casein Kinase I
prd-2, upf1 / prd-6
nonsense mediated decay
RNA-binding protein
SUZ domain
Online Access:https://elifesciences.org/articles/64007

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https://elifesciences.org/articles/64007

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