Kinetic Characterization and Inhibitor Screening of Pyruvate Kinase I From Babesia microti

Kinetic Characterization and Inhibitor Screening of Pyruvate Kinase I From Babesia microti

The apicomplexan Babesia microti is a main pathogenic parasite causing human babesiosis, which is one of the most widely distributed tick-borne diseases in humans. Pyruvate kinase (PYK) plays a central metabolic regulatory role in most living organisms and catalyzes the essentially irreversible step...

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Bibliographic Details
Main Authors: Xiaomeng An, Long Yu, Sen Wang, Yangsiqi Ao, Xueyan Zhan, Qin Liu, Yangnan Zhao, Muxiao Li, Xiang Shu, Fangjie Li, Lan He, Junlong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Microbiology
Subjects:
Babesia microti
pyruvate kinase I
inhibitors
kinetic characterization
inhibition assay
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.710678/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.710678/full

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