The role of c-kit and imatinib mesylate in uveal melanoma

The role of c-kit and imatinib mesylate in uveal melanoma

<p>Abstract</p> <p>Background</p> <p>Uveal melanoma (UM) is the most common primary intraocular tumor in adults, leading to metastasis in 40% of the cases and ultimately to death in 10 years, despite local and/or systemic treatment. The c-kit protein (CD117) is a membra...

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Bibliographic Details
Main Authors: Pereira Patricia, Odashiro Alexandre, Marshall Jean, Correa Zelia, Belfort Rubens, Burnier Miguel N
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2005-10-01
Series:Journal of Carcinogenesis
Subjects:
C-kit
CD117
melanoma
uveal
ocular
Gleevec<sup>®</sup>
Imatinib mesylate
Online Access:http://www.carcinogenesis.com/content/4/1/19

Internet

http://www.carcinogenesis.com/content/4/1/19

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