Postnatal and Adult Aortic Heart Valves Have Distinctive Transcriptional Profiles Associated With Valve Tissue Growth and Maintenance Respectively

Postnatal and Adult Aortic Heart Valves Have Distinctive Transcriptional Profiles Associated With Valve Tissue Growth and Maintenance Respectively

Heart valves are organized connective tissues of high mechanical demand. They open and close over 100,000 times a day to preserve unidirectional blood flow by maintaining structure-function relationships throughout life. In affected individuals, structural failure compromises function and often lead...

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Bibliographic Details
Main Authors: Emily Nordquist, Stephanie LaHaye, Casey Nagel, Joy Lincoln
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic valve
RNA-sequencing
mRNA
cell proliferation
extracellular matrix
postnatal
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00030/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00030/full

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