Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence of Neospora caninum

Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence of Neospora caninum

Neospora caninum causes abortions in cattle and nervous system dysfunction in dogs. Dense granular proteins (GRAs) play important roles in virulence; however, studies on NcGRA functions are limited. In the present study, multiple methods, including site-directed mutagenesis; CRISPR/Cas9 gene editing...

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Bibliographic Details
Main Authors: Jingquan Dong, Nan Zhang, Panpan Zhao, Jianhua Li, Lili Cao, Xiaocen Wang, Xin Li, Ju Yang, Xichen Zhang, Pengtao Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Veterinary Science
Subjects:
Neospora caninum
CRISPR
dense granules protein 2
intravacuolar network
immunofluorescence
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.634612/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.634612/full

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