Deletion of P2X2 and P2X3 receptor subunits does not alter motility of the mouse colon

Purinergic P2X receptors contribute to neurotransmission in the gut. P2X receptors are ligand-gated cation channels that mediate synaptic excitation in subsets of enteric neurons. The present study evaluated colonic motility in vitro and in vivo in wild type (WT) and P2X2 and P2X3 subunit knockout...

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Bibliographic Details
Main Authors: Matthew DeVries, Megan Vessalo, James J Galligan
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnent.2010.00001/full