Membrane Activity and Channel Formation of the Adenylate Cyclase Toxin (CyaA) of <i>Bordetella pertussis</i> in Lipid Bilayer Membranes

The Gram-negative bacterium <i>Bordetella pertussis</i> is the cause of whooping cough. One of its pathogenicity factors is the adenylate cyclase toxin (CyaA) secreted by a Type I export system. The 1706 amino acid long CyaA (177 kDa) belongs to the continuously increasing family of repe...

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Bibliographic Details
Main Authors: Oliver Knapp, Roland Benz
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/3/169