Photophysical and elecron-transfer reaction properties of tris(2,2’-bipyridine)ruthenium(II)-based inhibitors that covalently bound to the active site of chymotrypsin

Photophysical and elecron-transfer reaction properties of tris(2,2’-bipyridine)ruthenium(II)-based inhibitors that covalently bound to the active site of chymotrypsin

We have prepared two tris(2,2’-bipyridine)ruthenium(II) complex-based new chymotrypsin (CHT) inhibitors, [Ru(bpy)2(bsfbpy)]Cl2 and [Ru(bsfbpy)3]Cl2 {bsfbpy = 4-methyl-2,2′-bipyridine-4′-carboxylic acid [2-(4-benzenesulfonylfluoride)-ethyl]-amide}. They were covalently modified with Ser195 in the act...

Full description

Bibliographic Details
Main Authors: Hiroko Kimura, Natsuko Nagasato, Natsumi Kato, Mei Kojima, Chisato Enomoto, Eiji Nakata, Hiroshi Takashima
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Photochemistry and Photobiology
Subjects:
Chymotrypsin
Inhibitor
Ruthenium(II) Complex
Photoinduced Electron transfer
Charge separation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666469021000129

Internet

http://www.sciencedirect.com/science/article/pii/S2666469021000129

Similar Items