ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma

ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors that derive from the mucosal epithelium of the upper aerodigestive tract and present high mortality rate. Lack of efficient targeted-therapies and biomarkers towards patients’ stratification are caveats in the disease t...

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Bibliographic Details
Main Authors: Artemis Filippou, Henna Pehkonen, Piia-Riitta Karhemo, Juho Väänänen, Anni I. Nieminen, Juha Klefström, Reidar Grénman, Antti A. Mäkitie, Heikki Joensuu, Outi Monni
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
ANO1
head and neck cancer
p27<sup>Kip1</sup>
MCL1
intrinsic apoptosis
cell cycle
Online Access:https://www.mdpi.com/2072-6694/13/5/1170

Internet

https://www.mdpi.com/2072-6694/13/5/1170

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