Mammalian expression of virus-like particles as a proof of principle for next generation polio vaccines
Abstract Global vaccination programs using live-attenuated oral and inactivated polio vaccine (OPV and IPV) have almost eradicated poliovirus (PV) but these vaccines or their production pose significant risk in a polio-free world. Recombinant PV virus-like particles (VLPs), lacking the viral genome,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-01-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-020-00267-3 |