Sodium channels as targets for volatile anesthetics

The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells. Na+ channels are crucial to action potential in...

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Bibliographic Details
Main Authors: Karl F. Herold, Hugh C. Hemmings
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00050/full