Soluble Epoxide Hydrolase Inhibitory Activity of Selaginellin Derivatives from Selaginella tamariscina

Soluble Epoxide Hydrolase Inhibitory Activity of Selaginellin Derivatives from Selaginella tamariscina

Selaginellin derivatives 1–3 isolated from Selaginella tamariscina were evaluated for their inhibition of soluble epoxide hydrolase (sEH) to demonstrate their potential for the treatment of cardiovascular disease. All selaginellin derivatives (1–3) inhibited sEH enzymatic activity and PHOME hydrolys...

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Bibliographic Details
Main Authors: Jang Hoon Kim, Chong Woon Cho, Bui Huu Tai, Seo Young Yang, Gug-seoun Choi, Jong Seong Kang, Young Ho Kim
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
Selaginella tamariscina
Selaginellaceae
selaginellin
soluble epoxide hydrolase
non-competitive inhibition
Online Access:http://www.mdpi.com/1420-3049/20/12/19774

Internet

http://www.mdpi.com/1420-3049/20/12/19774

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