The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.
Numerous longevity genes have been discovered in model organisms and altering their function results in prolonged lifespan. In mammals, some have speculated that any health benefits derived from manipulating these same pathways might be offset by increased cancer risk on account of their propensity...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2289879?pdf=render |