Efficient Synthesis of Unprotected C-5-Aryl/Heteroaryl-2'-deoxyuridine via a Suzuki-Miyaura Reaction in Aqueous Media

Efficient Synthesis of Unprotected C-5-Aryl/Heteroaryl-2'-deoxyuridine via a Suzuki-Miyaura Reaction in Aqueous Media

Following our previous results on an environmentally benign one-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides under aqueous conditions, we investigate herein the Suzuki-Miyaura cross-coupling reactions of aryl and heteroaryl derivatives at the C5 position of u...

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Bibliographic Details
Main Authors: Nathalie Fresneau, Marie-Aude Hiebel, Luigi A. Agrofoglio, Sabine Berteina-Raboin
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
unnatural nucleosides
Suzuki-Miyaura coupling
aqueous conditions
Online Access:http://www.mdpi.com/1420-3049/17/12/14409

Internet

http://www.mdpi.com/1420-3049/17/12/14409

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