Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization.

The functional consequences of long-range nuclear reorganization were studied in a cell-by-cell analysis of gene expression and long-range chromosomal interactions in the Drosophila eye and eye imaginal disk. Position-effect variegation was used to stochastically perturb gene expression and probe nu...

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Bibliographic Details
Main Authors: Brian Harmon, John Sedat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1054879?pdf=render