Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.

Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.

Dendritic cells (DCs) subsets differ in precursor cell of origin, functional properties, requirements for growth factors, and dependence on transcription factors. Lymphoid-tissue resident CD8α(+) conventional DCs (cDCs) and CD11b(low/-)CD103(+) non-lymphoid DCs are developmentally related, each bein...

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Bibliographic Details
Main Authors: Brian T Edelson, Tara R Bradstreet, Wumesh KC, Kai Hildner, Jeremy W Herzog, Julia Sim, John H Russell, Theresa L Murphy, Emil R Unanue, Kenneth M Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3196467?pdf=render

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http://europepmc.org/articles/PMC3196467?pdf=render

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