Increased Sclerostin, but Not Dickkopf-1 Protein, Is Associated with Elevated Pulse Wave Velocity in Hemodialysis Subjects

Increased Sclerostin, but Not Dickkopf-1 Protein, Is Associated with Elevated Pulse Wave Velocity in Hemodialysis Subjects

Background: Sclerostin and Dickkopf-1 (Dkk-1) proteins are inhibitors of the canonical Wnt/β-catenin bone pathway. Pilot data suggest that sclerostin may be involved in vascular changes in chronic kidney disease (CKD), but data on the effects of Dkk-1 are scarce. This is the first study investigatin...

Full description

Bibliographic Details
Main Authors: Eirini Stavrinou, Pantelis A. Sarafidis, Charalampos Koumaras, Charalampos Loutradis, Panagiotis Giamalis, Konstantinos Tziomalos, Asterios Karagiannis, Aikaterini Papagianni
Format: Article
Language:English
Published: Karger Publishers 2019-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Sclerostin
Dickkopf-1 protein
Hemodialysis
Pulse wave velocity
Arterial stiffness
Online Access:https://www.karger.com/Article/FullText/501205

Internet

https://www.karger.com/Article/FullText/501205

Similar Items