Naofucong Ameliorates High Glucose Induced Hippocampal Neuron Injury Through Suppressing P2X7/NLRP1/Caspase-1 Pathway

Naofucong Ameliorates High Glucose Induced Hippocampal Neuron Injury Through Suppressing P2X7/NLRP1/Caspase-1 Pathway

P2X7/NLRP1/caspase-1 mediated neuronal injury plays an important role in diabetic cognitive impairment and eventually inflammatory cascade reaction. Chinese herbal compound Naofucong has been mainly used to treat cognitive disorders in Traditional Chinese Medicine The present study aimed to investig...

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Bibliographic Details
Main Authors: Guangchan Jing, Huanyuan Wang, Fengwei Nan, Yuqin Liu, Mengren Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
naofucong
pyroptosis
high glucose
hippocampal neurons
TCM
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.647116/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.647116/full

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