Novel <i>N</i>,<i>N</i>′-Disubstituted Acylselenoureas as Potential Antioxidant and Cytotoxic Agents

Novel <i>N</i>,<i>N</i>′-Disubstituted Acylselenoureas as Potential Antioxidant and Cytotoxic Agents

Selenium compounds are pivotal in medicinal chemistry for their antitumoral and antioxidant properties. Forty seven acylselenoureas have been designed and synthesized following a fragment-based approach. Different scaffolds, including carbo- and hetero-cycles, along with mono- and bi-cyclic moieties...

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Bibliographic Details
Main Authors: Ana Carolina Ruberte, Sandra Ramos-Inza, Carlos Aydillo, Irene Talavera, Ignacio Encío, Daniel Plano, Carmen Sanmartín
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Antioxidants
Subjects:
acylselenoureas
antioxidant
cytotoxicity
oxidative stress
radical scavenging
selenium
Online Access:https://www.mdpi.com/2076-3921/9/1/55

Internet

https://www.mdpi.com/2076-3921/9/1/55

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