Enterohemorrhagic Escherichia coli induce attaching and effacing lesions and hemorrhagic colitis in human and bovine intestinal xenograft models

SUMMARY Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important cause of diarrhea, hemorrhagic colitis and hemolytic uremic syndrome in humans worldwide. The two major virulence determinants of EHEC are the Shiga toxins (Stx) and the type III secretion system (T3SS), including the injected...

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Bibliographic Details
Main Authors: Lilach Golan, Erez Gonen, Simcha Yagel, Ilan Rosenshine, Nahum Y. Shpigel
Format: Article
Language:English
Published: The Company of Biologists 2011-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/1/86