Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions

Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions

Although polypurine tract (PPT)-primed initiation of plus-strand DNA synthesis in retroviruses and LTR-containing retrotransposons can be accurately duplicated, the molecular details underlying this concerted series of events remain largely unknown. Importantly, the PPT 3’ terminus must be accommoda...

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Bibliographic Details
Main Authors: Stuart F. J. Le Grice, John P. Marino, Daniele Fabris
Format: Article
Language:English
Published: MDPI AG 2009-11-01
Series:Viruses
Subjects:
retroviruses
LTR-retrotransposons
polypurine tract
plus strand DNA synthesis
NMR spectroscopy
single molecule spectroscopy
antiviral strategies
Online Access:http://www.mdpi.com/1999-4915/1/3/657/

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http://www.mdpi.com/1999-4915/1/3/657/

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