Reprogramming primordial germ cells into pluripotent stem cells.

<h4>Background</h4>Specification of primordial germ cells (PGCs) results in the conversion of pluripotent epiblast cells into monopotent germ cell lineage. Blimp1/Prmt5 complex plays a critical role in the specification and maintenance of the early germ cell lineage. However, PGCs can be...

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Bibliographic Details
Main Authors: Gabriela Durcova-Hills, Fuchou Tang, Gina Doody, Reuben Tooze, M Azim Surani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18953407/?tool=EBI