On the Stability and Degradation Pathways of Venetoclax under Stress Conditions

Venetoclax is an orally bioavailable, B-cell lymphoma-2 (BCL-2) selective inhibitor, used for the treatment of various types of blood cancers, such as chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). In this study we investigated the degradation of venetoclax under various st...

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Bibliographic Details
Main Authors: Nina Žigart, Martin Črnugelj, Janez Ilaš, Zdenko Časar
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/7/639