Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway

Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-κB Pathway

Recent studies have shown that dexmedetomidine exerts an anti-inflammatory effect by reducing serum levels of inflammatory factors, however, the up-stream mechanism is still unknown. The transcription factor NF-κB enters the nucleus and promotes the transcription of its target genes, including those...

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Bibliographic Details
Main Authors: Yan Huang, Yi Lu, Lei Zhang, Jia Yan, Jue Jiang, Hong Jiang
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
dexmedetomidine
NF-κB
IL-6
TNF-α
nerve block
Online Access:http://www.mdpi.com/1422-0067/15/3/4049

Internet

http://www.mdpi.com/1422-0067/15/3/4049

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