Phenotype-Agnostic Molecular Subtyping of Neurodegenerative Disorders: The Cincinnati Cohort Biomarker Program (CCBP)

Ongoing biomarker development programs have been designed to identify serologic or imaging signatures of clinico-pathologic entities, assuming distinct biological boundaries between them. Identified putative biomarkers have exhibited large variability and inconsistency between cohorts, and remain in...

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Main Authors: Andrea Sturchio, Luca Marsili, Joaquin A. Vizcarra, Alok K. Dwivedi, Marcelo A. Kauffman, Andrew P. Duker, Peixin Lu, Michael W. Pauciulo, Benjamin D. Wissel, Emily J. Hill, Benjamin Stecher, Elizabeth G. Keeling, Achala S. Vagal, Lily Wang, David B. Haslam, Matthew J. Robson, Caroline M. Tanner, Daniel W. Hagey, Samir El Andaloussi, Kariem Ezzat, Ronan M. T. Fleming, Long J. Lu, Max A. Little, Alberto J. Espay
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.553635/full